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The most recent releases include Wolves 5 reel video slot with a healthy RTP and stunning graphics. The other notable titles include Wolf Gold and Chilli Heat.<br><br>The goal of pragmatic trials is to simulate real-life scenarios and gain maximum credibility externally. They are usually commissioned by policymakers and practitioners in order to inform their decisions. They are also a good method of determining the causality between the intervention and its effects. However, they should not be used to substitute for explanatory trials.<br><br>The idea of pragmatism is controversial, and there are questions regarding whether pragmatic trials could replace tests for explanations or if they should serve as an alternative to them. Schwartz and Lellouch1 suggested an distinction between explanation-based studies, which confirm the physiological hypothesis or clinical hypothesis, as well as pragmatic trials, which inform policy and practice decision-making. They also suggested a framework dubbed PRECIS for pragmatic trials.2 The tool was designed to define the characteristics of a pragmatic study, including recruitment, design, implementation of the intervention and follow-up.<br><br>There is an encouraging increase in the number pragmatic trials that are published. A recent Medline query using the keywords pragmatic and naturalistic, limited to randomised controlled trials (RCTs), returned 34 articles. These are shown in red on Figure 2. This indicates that the health science community is becoming more sensitive to the subject of pragmatics. It is important to remember that the majority were conducted in primary care settings.
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