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They should not, however, be used to replace explanation studies.<br><br>The pragmatism concept is controversial and there are questions about whether pragmatic trials should be used to replace explanatory trials or complement them. Schwartz and Lellouch1 suggested a distinction between explanatory trials, which prove the validity of a clinical or physiological hypothesis and pragmatic trials, which guide the policy and practice of. They also suggested a framework dubbed PRECIS for pragmatic trials.2 This tool attempted to define the traits of a practical study that includes recruitment, design, delivery of the intervention and follow-up.<br><br>There is a positive increase in the number pragmatic trials that are published. A recent Medline query using the keywords naturalistic and pragmatic,  [https://bookmarkingbay.com/ 무료슬롯 프라그마틱] restricted to randomised controlled trials (RCTs), returned 34 articles. They are displayed in red on Figure 2. This indicates that the health sciences community is becoming more aware of the importance of pragmatic thinking. It is important to note that the majority of these studies were conducted in primary-care settings.