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Its software can be used on mobile devices and in a variety of languages. Despite its relatively young age, it has already established itself as a premier casino gaming platform. Wolves is one of the latest games which is a five-reel slot machine that has a high RTP and impressive graphics. Other notable games include Wolf Gold and Chilli Heat.<br><br>Pragmatic trials seek to replicate real-life situations and attain maximum external validity. They are usually requested by practitioners and policy makers to inform their decision making. They can also be used to assess the cause-effect relationship of an intervention and its effects. 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They also suggested a framework known as PRECIS for pragmatic trials.2 The tool was designed to define the characteristics of a pragmatic research study that includes recruitment, design, implementation of the intervention and its follow-up.<br><br>There is a growing increase in the number of pragmatic trials that have been published. A recent Medline search using the words pragmatic and naturalistic, which was restricted to randomised controlled trials (RCTs), returned 34 articles. They are displayed in red on Figure 2. This indicates that the health science community is becoming more acquaint to the issue of pragmatic thinking. It is important to keep in mind that the majority of these trials were conducted in primary care settings.
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