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Clinical trials that are designed to help inform practice in the real world are known as pragmatic trials. They are typically described as focusing on practical aspects of design, including the recruitment and 프라그마틱 게임 consent process, as well as adherence and the use routinely available equipment.

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Another example of a practical trial is the Home Blood Pressure Management (HBPM) study, which employed various investigators and participants from different geographical regions. This type of heterogeneity is required for pragmatic trials to be able to prove their validity and also reduces bias in the results. However, too much heterogeneity can cause problems with the design of the trial.

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The goal of pragmatic trials is to mimic real-life situations and achieve the highest level of validity externally. They are usually commissioned by policy makers and practitioners to guide their decision-making. They are also a good method of determining the causality between an intervention and its outcomes. They should, however, 프라그마틱 이미지 불법 [https://nerdgaming.science/wiki/15_amazing_facts_about_pragmatic_kr] not be used to replace explanation studies.

The pragmatism idea is controversial and there are doubts regarding whether pragmatic trials could replace explanatory tests or if they should serve as an addition to them. Schwartz and Lellouch1 suggested the distinction between explanation trials, which validate a physiological or clinical hypothesis as well as pragmatic trials, which guide the practice and policy decisions. They also proposed a framework called PRECIS for pragmatic trials.2 The tool was designed to define the traits of a practical study, including the recruitment, design, and delivery of the intervention and follow-up.

The number of pragmatic trials is increasing. A recent Medline query using the keywords naturalistic and pragmatic, restricted to randomised controlled trials (RCTs) returned 34 articles. These are shown in red on Figure 2. This is an indication that the health sciences community is becoming increasingly sensitized to the issue of pragmatism. It is important to keep in mind that the majority were conducted in primary-care settings.