How Much Do Pragmatic Free Trial Experts Make

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Pragmatic trials are those that are designed to inform real-world clinical practice. They are often focused on practical aspects of the research design, like the recruitment process and consent, adherence, and the use of standard equipment.

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Another example of a pragmatic trial is the Home Blood Pressure Management (HBPM) study, which utilized different investigators and participants from different geographic areas. This type of heterogeneity, which is essential for a pragmatic trial to be reliable and lessen the chance of bias is also essential. However too much heterogeneity could cause issues with the design of the trial.

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Legality

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The aim of pragmatic trials is to mimic real-life scenarios and gain maximum credibility externally. They are usually requested by practitioners and policy makers to guide their decision-making. They can be used to determine the causal relationship between an intervention and its results. They should not, however be used to replace explanatory studies.

The concept of pragmatism is controversial and there are doubts about whether pragmatic trials should replace explanatory trials or complement them. Schwartz and Lellouch1 suggested a distinction between explanatory trials, which prove the clinical or physiological hypothesis and pragmatic trials that inform policy and practice decisions. They also suggested a framework known as PRECIS for pragmatic trials.2 This tool attempted to define the elements of a practical study which includes recruitment, design, delivery of the intervention and its follow-up.

The number of pragmatic trials is increasing. A recent Medline query that used the words pragmatic and naturalistic, limited to randomised controlled trials (RCTs), returned 34 articles. They are displayed in red on Figure 2. This indicates that the health sciences community is becoming more aware of the importance of pragmatism. It is important to note that the majority of these trials were conducted in primary care settings.