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Studies designed to provide insight into clinical practice in the real world are known as pragmatic trials. They are often characterized as focusing on practical aspects of study design that include recruitment and consent, adherence and the use routinely available equipment.

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A pragmatic study that involves various investigators and participants from different geographical areas is the Home Blood Pressure Management study (HBPM). This type of heterogeneity is essential for pragmatic trials to be valid and helps to reduce bias in the results. However, too much heterogeneity, can cause problems with the design of the trial.

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The goal of pragmatic trials is to simulate real-life situations and achieve maximum credibility externally. Usually, 프라그마틱 슬롯 환수율 they are requested by practitioners and policymakers to help guide their decisions. They can be used to determine the causality of an intervention and its effects. They should, however, not be used to replace explanation studies.

The idea of pragmatism is controversial and there are doubts regarding whether pragmatic trials could replace tests for explanations or if they should serve as a complement to them. Schwartz and Lellouch1 made an distinction between explanation-based studies, which support a physiological hypothesis or clinical hypothesis, as well as pragmatic trials, that inform the practice and policy decision-making. They also suggested a framework dubbed PRECIS for pragmatic trials.2 The tool was designed to define the traits of a pragmatic study which includes the recruitment, design, and delivery of the intervention and 프라그마틱 무료체험 슬롯버프 its follow-up.

The number of pragmatic trials is increasing. A recent Medline search using the keywords naturalistic and pragmatic, which was limited to randomized controlled trials (RCTs) resulted in 34 articles, which are shown in red in Figure 2. This is a sign that the health science community is becoming more sensitive to the issue of pragmatism. It is important to remember, however, that the majority of these studies were conducted in primary-care settings.