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Clinical trials that are designed to help inform practice in the real world are known as pragmatic trials. They are usually focused on the practical aspects of the research design, like the recruitment and consent process in adherence, as well as the use of routinely available equipment.

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A practical trial that employs a variety investigators and includes participants from diverse geographical locations is the Home Blood Pressure Management study (HBPM). This kind of heterogeneity is required for practical trials to be valid, and it also helps to reduce bias in the results. A high degree of heterogeneity, however can result in problems with the trial design.

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The purpose of pragmatic trials is to simulate real-life scenarios and gain maximum credibility externally. Usually, they are ordered by policymakers and practitioners in order to inform their decisions. They also provide a useful method of determining the causality between an intervention and 프라그마틱 슬롯 체험 its outcomes. However, they should not be used in lieu for explanatory trials.

The concept of pragmatism is controversial, and there are questions regarding whether pragmatic trials could be used to replace explanation tests or if they are an addition to them. Schwartz and Lellouch1 made a distinction between explanatory studies, which prove the physiological hypothesis or clinical hypothesis, and pragmatic trials, 프라그마틱 슬롯 추천 that inform the decision-making process for policy and practice. They also suggested a framework dubbed PRECIS for 프라그마틱 정품 pragmatic trials.2 This tool attempted to define the elements of a pragmatic research study that includes the recruitment, design, and delivery of the intervention and follow-up.

There is a positive increase in the number of pragmatic trials that have been published. A recent Medline search using the keywords naturalistic and pragmatic, which was limited to randomized controlled trials (RCTs), yielded 34 articles, which are shown in red in Figure 2. This indicates that the health sciences community has become more aware of the importance of pragmatism. It is important to keep in mind that the majority of these trials were conducted in primary care settings.