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Studies designed to provide insight into clinical practice in the real world are called pragmatic trials. They are often characterized as a focus on the practical aspects of designing a study that include the recruitment and consent process, as well as adherence and the use of standard equipment.
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A pragmatic study that involves a variety investigators and includes participants from diverse geographical locations is the Home Blood Pressure Management study (HBPM). This type of heterogeneity, which is vital for a pragmatic trial to be reliable and lessen the chance of bias is also essential. However excessive heterogeneity could cause issues with the design of the trial.
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The purpose of pragmatic trials is to replicate real-life scenarios and gain maximum validity externally. They are typically commissioned by practitioners and policy makers to guide their decision-making. They can also be a great method of determining the causal relationship between the intervention and 프라그마틱 슬롯버프 its effects. However, they should not be used to substitute for the use of explanation studies.
The concept of pragmatism is controversial, and there are questions about whether pragmatic trials can replace tests for explanations or if they are an alternative to them. Schwartz and Lellouch1 suggested the distinction between explanatory trials, which confirm the clinical or physiological hypothesis and pragmatic trials, which inform the policy and practice of. They also proposed an approach to pragmatic trials, which they called PRECIS.2 This tool sought to define the features of a pragmatic study, 프라그마틱 정품확인 including the recruitment process, the design and 프라그마틱 슬롯 추천 implementation of the intervention, as well as the follow-up.
The number of pragmatic trials is increasing. A recent Medline search using the terms naturalistic and pragmatic, which was limited to controlled trials randomized to control (RCTs), yielded 34 articles, which are shown in red in Figure 2. This suggests that the health sciences community is becoming more aware of the importance of pragmatism. It is important to keep in mind that the majority of these studies were conducted in primary-care settings.