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Trials designed to inform clinical practice in the real world are known as pragmatic trials. They are typically described as a focus on the practical aspects of design, including recruitment and consent, adherence and the use of standard equipment.

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Pragmatic Play, known for its slot machine games also offers table-games like Bitcoin baccarat or Roulette. They offer more than 12 licensed games and their software is known for being reliable and secure. Their software is available in several languages and offer several betting options including live dealer tables.

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Another example of a trial that is pragmatic is the Home Blood Pressure Management (HBPM) study, which employed a variety of investigators and had participants from different geographical regions. This type of heterogeneity which is essential for pragmatic trials to be reliable and lessen the chance of bias, is also necessary. However, too much heterogeneity can result in issues with the design of the trial.

Pragmatic Play is also a major player on the live casino market, providing a wide selection of classic table games such as Blackjack and Roulette in various variations. The live studios of the company in Romania and Malta offer a real-life gambling experience for customers, as well as a full suite of virtual betting options. The company also has several game shows that make online gambling exciting and interactive. Some of these shows are telecast live and others feature famous personalities in the field.

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Pragmatic trials aim to mimic real-world situations and have the highest external validity. They are typically commissioned by practitioners and policy makers to inform their decision making. They are also a good method of determining the causal relationship between an intervention and its results. They should, however, not, be used to replace explanation studies.

The idea of pragmatism is controversial and there are concerns about whether pragmatic trials should replace explanatory tests or if they are an addition to them. Schwartz and Lellouch1 made an distinction between explanation-based studies, which prove the validity of a physiological or clinical hypothesis, and pragmatic trials, that inform the decision-making process for policy and practice. They also suggested a framework dubbed PRECIS for pragmatic trials.2 The tool was designed to define the elements of a pragmatic study which includes recruitment, design, delivery of the intervention and follow-up.

The number of pragmatic trials is increasing. A recent Medline query that used the words naturalistic and pragmatic, restricted to randomised controlled trials (RCTs), 프라그마틱 홈페이지 슬롯 팁 (https://fsquan8.cn) returned 34 articles. These are highlighted in red on Figure 2. This indicates that the health sciences community has become more aware of the importance of pragmatism. It is important to remember, however, that the majority were conducted in primary-care settings.