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Studies designed to provide insight into clinical practice in the real world are called pragmatic trials. They are typically described as a focus on the practical aspects of designing a study which include the recruitment and consent process, as well as adherence and the use of routinely available equipment.
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Another example of a pragmatic trial is the Home Blood Pressure Management (HBPM) study, which used a variety of investigators and included participants from different geographical regions. This kind of heterogeneity is essential for 프라그마틱 슬롯버프 practical trials to be valid and also helps reduce bias in the results. However too much heterogeneity could result in problems with the design of the trial.
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The aim of pragmatic trials is to replicate real-life scenarios and to achieve the highest level of validity externally. They are usually requested by policy makers and practitioners to inform their decision making. They can also be used to assess the causality of an intervention and its effects. They should, however, not be used to replace the need for explanation studies.
The concept of pragmatism is controversial, and there are doubts about whether pragmatic trials should replace explanatory trials or complement them. Schwartz and Lellouch1 suggested the distinction between explanation studies, which support the validity of a physiological or clinical hypothesis, as well as pragmatic trials, that inform policy and practice decision-making. They also suggested a framework dubbed PRECIS for pragmatic trials.2 The tool was designed to define the traits of a pragmatic study which includes recruitment, 프라그마틱 슬롯 추천 (Https://Ayers-Jespersen-3.Blogbright.Net/How-Do-You-Explain-Pragmatic-Authenticity-Verification-To-A-Five-Year-Old) design, implementation of the intervention, and follow-up.
The number of pragmatic trials is increasing. A recent Medline search using the words naturalistic and pragmatic, 프라그마틱 공식홈페이지 restricted to randomised controlled trials (RCTs) returned 34 articles. These are shown in red on Figure 2. This is an indication that the health sciences community is becoming increasingly sensitized to the issue of pragmatism. It is important to keep in mind that the majority of these studies were conducted in primary care settings.