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Pragmatic trials are those that are designed to provide information for real-world clinical practice. They are often characterized as focusing on practical aspects of study design, including the recruitment and consent process, as well as adherence and the use routinely available equipment.
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A pragmatic trial that uses different investigators and participants from different geographical areas is the Home Blood Pressure Management study (HBPM). This type of heterogeneity which is essential for pragmatic trials to be reliable and lessen the chance of bias is also essential. Too much heterogeneity, however can result in problems with the design of the trial.
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Legality
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The aim of pragmatic trials is to replicate real-life situations and achieve maximum credibility externally. Usually, they are ordered by policymakers and practitioners to help guide their decisions. They also provide a useful way to identify the causal relationship between an intervention and its outcomes. However, they should not be used to substitute for the use of explanation studies.
The concept of pragmatism is controversial and there are doubts about whether pragmatic trials should replace or complement them. Schwartz and Lellouch1 made the distinction between explanation studies, which confirm a physiological hypothesis or clinical hypothesis, as well as pragmatic trials, that inform the decision-making process for 무료슬롯 프라그마틱 policy and practice. They also suggested a framework dubbed PRECIS for pragmatic trials.2 This tool tried to define the traits of a pragmatic research study which includes the recruitment, design, and delivery of the intervention, and follow-up.
The number of pragmatic trials is growing. A recent Medline query using the keywords naturalistic and pragmatic, restricted to randomised controlled trials (RCTs), returned 34 articles. These are highlighted in red on Figure 2. This indicates that the health sciences community is becoming more aware of the importance of pragmatic thinking. It is important to keep in mind that the majority of these studies were conducted in primary care settings.