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Clinical trials that are designed to help inform practice in the real world are known as pragmatic trials. They are typically described as a focus on the practical aspects of designing a study which include recruitment and consent, adherence and the use routinely available equipment.

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Another example of a trial that is pragmatic is the Home Blood Pressure Management (HBPM) study, which utilized a variety of investigators and had participants from different geographic areas. This type of heterogeneity is essential for practical trials to be valid, and it also helps reduce the chance of bias in the results. However, too much heterogeneity can result in problems with the design of the trial.

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The goal of pragmatic trials is to mimic real-life scenarios and gain maximum credibility externally. They are usually commissioned by policymakers and practitioners to inform their decisions. They are also a good way to identify the causality between an intervention and its results. They should not, however, be used to replace explanatory studies.

The pragmatism idea is controversial and there are concerns regarding whether pragmatic trials could replace explanatory tests or if they should serve as a complement to them. Schwartz and Lellouch1 suggested the distinction between explanation trials, which validate a physiological or clinical hypothesis, and pragmatic trials that inform the practice and policy decisions. They also proposed an approach to pragmatic trials, which they called PRECIS.2 This tool sought to define the features of a pragmatic study that include the recruitment process, 무료슬롯 프라그마틱 정품 확인법 (https://Pragmatickr90987.blogginaway.com) the design and implementation of the intervention, and the follow-up.

There is an encouraging trend in the number of pragmatic trials published. A recent Medline search using the terms naturalistic and pragmatic, which was limited to controlled trials that are randomized (RCTs), yielded 34 articles, which are shown in red in Figure 2. This is a sign that the health science community is becoming increasingly sensitized to the issue of pragmatics. However, it is important to keep in mind that the majority of these studies were conducted in primary care settings.