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Clinical trials that are designed to help inform practice in the real world are called pragmatic trials. They are often described as focusing on practical aspects of design, including the recruitment and consent process, as well as adherence and the use of routinely available equipment.

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A practical trial that employs various investigators and participants from different geographical areas is the Home Blood Pressure Management study (HBPM). This type of heterogeneity which is vital for a pragmatic trial to be reliable and reduce bias in results, is also necessary. Too much heterogeneity, however can result in problems with the trial design.

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The aim of pragmatic trials is to mimic real-life situations and 프라그마틱 슬롯 무료체험 achieve maximum credibility externally. They are usually ordered by policymakers and practitioners to help inform their decisions. They can also be used to determine the cause-effect relationship of an intervention and its results. They should, however, not, be used to replace explanation studies.

The concept of pragmatism is controversial, and there are questions about whether pragmatic trials should replace or complement them. Schwartz and Lellouch1 proposed the distinction between explanation studies, which prove the physiological hypothesis or clinical hypothesis, and pragmatic trials that aid in policy and practice decision-making. They also suggested a framework dubbed PRECIS for pragmatic trials.2 This tool attempted to define the characteristics of a practical study, including the recruitment, design, and delivery of the intervention and its follow-up.

There is a positive increase in the number pragmatic trials published. A recent Medline search using the terms naturalistic and pragmatic, limited to controlled trials that are randomized (RCTs), yielded 34 articles, shown in red in Figure 2. This indicates that the health sciences community is becoming increasingly sensitized to the subject of pragmatism. However, 프라그마틱 사이트 it is important to remember that the majority of these studies were conducted in primary care settings.