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Studies designed to provide insight into clinical practice in the real world are called pragmatic trials. They are typically described as focusing on practical aspects of study design which include the recruitment and consent process, as well as adherence and the use routinely available equipment.
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Another example of a pragmatic trial is the Home Blood Pressure Management (HBPM) study, which employed a variety of investigators and included participants from different geographic areas. This type of heterogeneity is required for practical trials to be valid, and it also reduces bias in the results. However excessive heterogeneity could result in issues with the design of the trial.
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The goal of pragmatic trials is to replicate real-life scenarios and to achieve maximum credibility externally. They are usually commissioned by policy makers and 프라그마틱 정품 사이트 practitioners to inform their decision making. They can also be a great method to determine the causality between an intervention and its outcomes. However, 프라그마틱 슬롯 하는법 정품 확인법 (https://ai-Db.science/wiki/10_telltale_signals_you_should_know_to_know_before_you_buy_pragmatic_product_authentication) they shouldn't be used to substitute for explanation trials.
The pragmatism idea is controversial and there are doubts about whether pragmatic trials should replace explanatory trials or complement them. Schwartz and Lellouch1 proposed a distinction between explanatory studies, which support the physiological hypothesis or clinical hypothesis, as well as pragmatic trials, which inform the practice and policy decision-making. They also proposed a framework called PRECIS for pragmatic trials.2 This tool attempted to define the traits of a pragmatic research study, including recruitment, design, 프라그마틱 이미지 체험 (https://freeman-moesgaard-2.technetbloggers.de) implementation of the intervention and follow-up.
There is a growing trend in the number of pragmatic trials published. A recent Medline search using the words naturalistic and pragmatic, restricted to randomised controlled trials (RCTs) returned 34 articles. These are shown in red on Figure 2. This is a sign that the health science community is becoming more acquaint to the issue of pragmatic thinking. However, it is important to note that the majority of these trials were conducted in primary care settings.